연구 동향

Bone2026-11-02

GLP-1 수용체 작용제의 골대사에 대한 영향: 주로 제1세대 약물의 무작위 위약 대조 임상시험에 대한 체계적 문헌고찰 및 메타분석

The effect of glucagon-like peptide-1 receptor agonists on bone metabolism: A systematic review and meta-analysis of randomized placebo-controlled trials of predominantly first-generation agents

Indian journal of pharmacology2026-11-02

티르제파타이드 관련 심각한 등용적 저나트륨혈증: 항이뇨호르몬 부적절 분비 증후군과 부합하는 생화학적 특징

Tirzepatide-associated severe euvolemic hyponatremia with syndrome of inappropriate antidiuretic hormone secretion-compatible biochemical features

Molecular pharmaceutics2026-11-02

[18F]AlF-NOTA-Asp2-티르제파타이드를 이용한 GLP-1 수용체 및 GIPR 이중 표적 PET 영상

PET Imaging of Dual GLP-1R and GIPR Targeting with [18F]AlF-NOTA-Asp2-Tirzepatide

Balkan medical journal2026-11-02

GLP-1 Receptor Agonists Versus Empagliflozin or Dapagliflozin in the MASLD-Heart Failure Phenotype: An Exploratory Propensity-Matched Cohort Study

Annals of human biology2026-11-02

Evolutionary perspectives on GLP-1 receptor agonists and the modern obesity, sedentary behaviour, and loneliness epidemics

Kidney research and clinical practice2026-11-02

Effect of combined sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor agonist therapy in patients with chronic kidney disease: a real-world analysis

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2026-11-01

GLP-1 Receptor Agonist Effects on Food-Related Cognition: A Cognitive Neuroscience Framework

Current problems in cardiology2026-11-01

2형 당뇨병 환자의 심박동기 삽입 시 GLP-1 수용체 작용제 및 SGLT2 억제제 사용과 치료 결과의 연관성

Association of GLP-1 receptor agonist and SGLT2 inhibitor use with outcomes in patients with type 2 diabetes undergoing pacemaker implantation

International journal of biological macromolecules2026-11-01

알부민 결합 영역 융합 GLP-1 유사체의 개발: 구조적 통찰, 수용체 활성화 및 기능 특성화

Development of an albumin-binding domain-fused GLP-1 analog: Structural insights, receptor activation, and functional characterization

Diabetology international2026-10-31

Baseline depressive-symptom severity and divergent psychological trajectories during GIP and/or GLP-1 receptor agonist therapy: a prospective ecological momentary assessment study

Diabetology international2026-10-31

Baseline monocyte GIP receptor mRNA expression is associated with reductions in body weight and FIB-4 index after switching to tirzepatide in patients with type 2 diabetes

Journal of diabetes and metabolic disorders2026-10-31

Efficacy and safety of semaglutide versus placebo in adults with overweight or obesity without diabetes: updated meta-analysis of randomized trials

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2026-10-31

MASLD 환자에서 GLP-1 수용체 작용제 치료와 심혈관 결과의 연관성: 중개 연구

Association of GLP-1 receptor agonist therapy with cardiovascular outcomes in patients with MASLD: A translational study

Gynecologic oncology2026-10-31

자궁내막암 비만 환자에서 글루카곤유사펩타이드-1 수용체 작용제 사용 추세

Trends in use of glucagon-like peptide-1 receptor agonists in obese patients with endometrial cancer

Endocrine2026-10-31

2형 당뇨병에서 기저 인슐린과 GLP-1 수용체 작용제의 고정 비율 병합투여의 혈당 조절 및 체중 감소 효과: 체계적 문헌고찰 및 네트워크 메타분석

Glycemic control and weight loss benefits of fixed-ratio combinations of basal insulins and GLP1 receptor agonists in type 2 diabetes: A systematic review and network meta-analysis

Reviews in endocrine & metabolic disorders2026-10-31

2형 당뇨병 성인의 포괄적 관리에서 영양 권장사항의 문화적 적응: 갱신된 문화간 당뇨병 영양 알고리즘(tDNA) 프레임워크

Cultural adaptation of nutritional recommendations in the comprehensive care of adults with type 2 diabetes: An updated transcultural diabetes nutrition algorithm (tDNA) framework

bioRxiv (프리프린트)2026-10-31프리프린트 · 동료심사 전

간 ILC1 면역감시 회피가 유방암 간 전이를 유도

Evasion of Hepatic ILC1 Immunosurveillance Drives Breast Cancer Liver Metastasis

Medicina clinica2026-10-30

심부전·제2형 당뇨병·비만 노령 환자에서 세마글루타이드의 일상생활활동 및 건강 상태 개선: 실제 임상 연구

Activities of daily living and health status benefits of semaglutide in very old patients with heart failure, type 2 diabetes, and obesity: Real-world practice study

British journal of haematology2026-10-30

GLP-1 수용체 작용제 및 이중 작용제와 혈액종양의 위험: 메타분석

Risk for haematological malignancies with glucagon-like peptide-1 receptor agonists and dual agonists: A meta-analysis

The lancet. Diabetes & endocrinology2026-10-30

비만증이 있는 일본인 참가자에서 경구 orforglipron의 효능 및 안전성 (ATTAIN-J): 이중맹검, 무작위배정, 위약 대조, 병렬군, 3상 임상시험

Efficacy and safety of oral orforglipron in Japanese participants with obesity disease (ATTAIN-J): a double-blind, randomised, placebo-controlled, parallel-group, phase 3 trial

The lancet. Diabetes & endocrinology2026-10-30

일본인 비만 환자를 위한 경구 소분자 GLP-1 수용체 작용제

Oral small-molecule GLP-1 receptor agonist for obesity in people from Japan

Med (New York, N.Y.)2026-10-30

알츠하이머병 및 파킨슨병 임상시험을 위한 메커니즘 기반 대사 엔드타입

Metabolic endotyping for mechanism-informed Alzheimer's and Parkinson's disease trials

Journal of the American Heart Association2026-10-30

비만 심부전과 보존된 박출계수에서 GLP-1 수용체 작용제

Glucagon-Like Peptide-1 Receptor Agonists in Obese Heart Failure With Preserved Ejection Fraction

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology2026-10-30

고안드로겐혈증 인슐린 저항성 여성에서 GLP-1 수용체 작용제의 대사, 호르몬 및 생식 관련 영향: 체계적 문헌고찰

Metabolic, hormonal, and reproductive effects of GLP-1 receptor agonizts in hyperandrogenic insulin-resistant women: a systematic review

Expert review of clinical pharmacology2026-10-30

대사 치료에서 중독 관리로: 물질 사용 장애에서의 GLP-1 수용체 작용제 임상 약리학 로드맵

From metabolic therapy to addiction care: a clinical pharmacology roadmap for GLP-1 receptor agonists in substance use disorders

Molecular medicine reports2026-10-30

암에서 GLP-1 수용체의 역할: 기전과 약리학적 중재 (리뷰)

Role of glucagon‑like peptide‑1 receptor in cancer: Mechanisms and pharmacologic intervention (Review)

Current opinion in endocrinology, diabetes, and obesity2026-10-29

비만의 비뇨기과적 임상 양상

Urological manifestations in obesity

Current opinion in endocrinology, diabetes, and obesity2026-10-29

비만과 골취약성: 기존 패러다임의 재검토

Obesity and skeletal fragility: revisiting an old paradigm

Journal of vascular surgery2026-10-29

GLP-1 수용체 작용제가 복부 대동맥류 환자에서 파열, 심장 사건 및 사망률 감소

GLP-1 Receptor Agonists Decrease the Rate of Rupture, Cardiac Events, and Death in Patients with Abdominal Aortic Aneurysms

Diabetes research and clinical practice2026-10-29

비만 관련 암 생존자에서 세마글루타이드 대 다른 GLP-1 수용체 작용제 및 심혈관 위험

Semaglutide versus other GLP-1 RAs and cardiovascular risk in obesity-related cancer survivors

Immunity2026-10-29

성장인자 VEGF-B가 장 Tfh 세포의 줄기성을 유지하여 Taurinivorans 과다증식과 미생물 유도 비만을 제한

Growth factor VEGF-B sustains intestinal Tfh cell stemness to restrict Taurinivorans outgrowth and microbiota-driven obesity

Drugs2026-10-29

경도로 감소되거나 보존된 좌심실 박출량을 가진 심부전에 대한 약물 치료의 비교 효과: 무작위 대조 시험의 체계적 검토 및 네트워크 메타분석

Comparative Effects of Pharmacological Treatment on Heart Failure with Mildly Reduced or Preserved Ejection Fraction: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials

Endocrine2026-10-29

세마글루타이드와 티르제파타이드의 비교 이상사례 보고 패턴: FAERS의 비례성 분석

Comparative adverse-event reporting patterns of semaglutide and tirzepatide: a disproportionality analysis of FAERS

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026-10-29

다분비 대사성 난소 증후군에서의 장-난소 축: 기전, 미생물총 불균형, 및 신흥 치료 전략

The gut-ovary axis in polyendocrine metabolic ovarian syndrome: Mechanisms, microbiome dysbiosis, and emerging therapeutic strategies

Journal of the American Geriatrics Society2026-10-29

고령 성인의 비만 약물: 안전하고 환자 중심의 처방을 위한 노인의학 5Ms 프레임워크

Obesity Medications in Older Adults: A Geriatrics 5Ms Framework for Safe and Patient-Centered Prescribing

Alzheimer's & dementia (New York, N. Y.)2026-10-28

분타네탑과 둘라글루타이드의 병용 투여가 알츠하이머병 마우스 모델에서 시냅스 기능장애 및 기억상실을 억제

Combined administration of buntanetap and dulaglutide counteracts synaptic dysfunction and memory loss in an Alzheimer's disease mouse model

Clinics in dermatology2026-10-28

GLP-1 수용체 작용제와 당뇨병성 발: 기전, 임상 근거 및 실제적 고려사항

GLP-1 Receptor Agonists and the Diabetic Foot: Mechanisms, Clinical Evidence, and Practical Considerations

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists2026-10-28

수용체 구조에서 임상 결과 성숙도까지: 다중기관 인크레틴 치료를 위한 임상 틀

From receptor architecture to outcome maturity: a clinical framework for multiorgan incretin therapy

British journal of pharmacology2026-10-28

GLP-1 수용체 활성화는 만성 편두통 유사 행동을 감소시킨다: 아편유사제 및 엔도카나비노이드 관련 경로의 성별 특이적 조절

GLP-1 receptor activation attenuates chronic migraine-like behaviour: Sex-specific modulation of opioid- and endocannabinoid-related pathways

Journal of diabetes science and technology2026-10-28

2형 당뇨병에서 GLP-1 수용체 작용제 대 활성 비교약물의 다중계통 결과: 다기관 표적시험 모방

Multisystem Outcomes of GLP-1 Receptor Agonists Versus Active Comparators in Type 2 Diabetes: A Multicenter Target Trial Emulation